Uremia is the final stage in the continuous development of chronic renal failure, and it is the advanced stage of chronic renal failure. The glomerular filtration rate is <10 mL/min, and the blood creatinine is >707 μmol/L. At this time, the clinical manifestations and blood biochemical abnormalities are very abnormal. Dialysis is needed, and complications can occur.
In the past, uremia was mainly caused by glomerulonephritis, but now it has become diabetes and hypertension, both of which can cause kidney disease.
All in all, uremia is a group of clinical syndromes mainly due to the decline in the filtration function of the kidneys and the decline in the ability to detoxify, including hypoxemia, electrolyte disorders, neurological symptoms, anemia, low calcium, and digestive symptoms such as nausea, vomiting, fatigue, dizziness, decreased urine output.
The early symptoms of uremia are as follows:
1. Drowsiness and fatigue: This may be a very early manifestation of uremia. Many patients with uremia will have symptoms of anemia in the early stage. Patients with anemia generally have poor complexion and pale lip and nails. Therefore, the yellowing of the complexion is one of the pre-symptoms of uremia.
2. Changes in urine output: due to the decline in the filtration function of the kidneys, some patients will gradually decrease their urine output as the disease progresses. Even if the urine output is normal, because the toxins eliminated in the urine are reduced and the quality is reduced, too much waste can not be discharged from the body, but to a certain extent, the urine output cannot fully explain the quality of the kidney function.
3. Poor appetite: Patients with uremia may have symptoms of the digestive system. The earliest symptoms of uremia are loss of appetite or indigestion, which is caused by the retention of urinary toxins, which affects digestive function. These symptoms are probably due to the urease of bacteria in the intestine breaking down urea into ammonia, which irritates the gastrointestinal mucosa and causes inflammation.
4. Diabetes: One of the serious complications of diabetic patients is called diabetic nephropathy, but many diabetic patients ignore this aspect. Early treatment of diabetic nephropathy can achieve better results. People with diabetes should monitor the changes in the kidneys.
5. Nocturia, polyuria, and light urine (the color becomes lighter, even like clear water).
6. Irregular menstruation in women.
7. The body is swollen, the kidney function is continuously reduced due to the damage of urinary toxins, and the excess water in the body is also difficult to discharge. In the early stage of uremia, local swelling of the ankles and eyelids may occur.
People who are usually susceptible to uremia include: people with kidney disease are more likely to get uremia, and people with high blood pressure and diabetes are more likely to get uremia. People with urinary tract infections and AIDS are also prone to uremia. Once the elderly encounter an accident, it is easy to cause further damage to the kidney function. These people should pay more attention to the changes in their bodies.
After understanding the early symptoms of uremia, I hope to arouse the vigilance of many patients and friends, so that the disease can be detected in time, controlled in time, and prevented from getting worse.